Comparative proteomic analysis provides insight into the molecular mechanism of vegetative growth advantage in allotriploid Populus

Comparative proteomic analysis provides insight into the molecular mechanism of vegetative growth advantage in allotriploid Populus

An integrative systems genetic analysis of mammalian lipid metabolism., azide free, Default, Effect of Substrate Topography and Chemistry on Human Mesenchymal Stem Cell Markers: A Transcriptome Study., elisa, Goat, Hamster, Mammal, Mink, Mouse, Opossum, Orangutan, pcr, Pig, Pigeon, Plant, Rat, SQSTM1/p62-Directed Metabolic Reprogramming Is Essential for Normal Neurodifferentiation., Yeast / By

Though allotriploid poplar exhibits a salient vegetative growth advantage that impacts biomass and lumber yield, the proteomic knowledge of Populus allotriploids haven’t been scrutinized for figuring out the underlying molecular mechanisms. We performed a large-scale label-free proteomics profiling of the fifth, 10th, and 25th leaves of allotriploids and diploids, and recognized 4587 protein teams. Among 932 differentially expressed proteins (DEPs), 22 are transcription elements (TFs) that would regulate vegetative growth advantage in allotriploids.

The DEPs concerned in gentle response, Calvin cycle, and photorespiration, protein synthesis, sucrose synthesis, starch synthesis, and starch decomposition displayed elevated expression in Populus allotriploids. However, the DEPs functioning in sucrose decomposition, tricarboxylic acid (TCA) cycle, and protein degradation exhibited considerably downregulated expression. The alternations of these DEPs augmented effectivity of photosynthesis, carbon fixation, sucrose and starch accumulation, and decreased capability of carbohydrate consumption, resulting in bigger quantity of biomass and vigorous growth in Populus allotriploids. Sorafenib is usually used to deal with superior human hepatocellular carcinoma (HCC). However, medical efficacy has been restricted by drug resistance.

In this research, we used label-free quantitative proteomic analysis to systematically examine the underlying mechanisms of sorafenib resistance in HCC cells. A complete of 1709 proteins have been confidently quantified. Among them, 89 have been differentially expressed, and extremely enriched in the processes of cell-cell adhesion, detrimental regulation of apoptosis, response to drug and metabolic processes involving in sorafenib resistance. Notably, folate receptor α (FOLR1) was discovered to be considerably upregulated in resistant HCC cells.

In addition, in-vitro research confirmed that overexpression of FOLR1 decreased the sensitivity of HCC cells to sorafenib, whereas siRNA-directed knockdown of FOLR1 elevated the sensitivity of HCC cells to sorafenib. Growing proof means that the pluripotent state of mesenchymal stem cells (MSCs) depends on particular native microenvironmental cues comparable to adhesion molecules and growth elements. Fibronectin (FN), fibroblast growth issue 2 (FGF2), and bone morphogenetic protein 4 (BMP4) are the key gamers in the regulation of stemness and lineage dedication of MSCs.

Therefore, this research was designed to analyze the pluripotency and multilineage differentiation of bone marrow-derived MSCs (BMSCs) with the introduction of FN, FGF-2, and BMP4 and to determine the metabolic and proteomic cues concerned in stemness upkeep.

How to successfully put together a pattern for bottom-up proteomic analysis of nanoparticle protein corona? A essential evaluate

Since the curiosity in the biomedical purposes of inorganic nanoparticles (NPs) has quickly grown over the final many years, there’s a want for a radical characterization of bio-nano interactions. NPs launched to the physique (principally intravenously) encounter plasma proteins, that immediately create a so-called “protein corona” on the NPs floor, giving the nanomaterial a brand new organic id. Type of the proteins that work together with NPs might have an effect on the in vivo destiny of NPs. For that purpose, it’s notably necessary to ascertain analytical strategies succesful of corona protein identification.

Bottom-up proteomics is most frequently used for that function. An important half of the experiment is pattern preparation, as it’s already confirmed that completely different protocols might result in distinct outcomes. This evaluate is aimed toward offering a characterization of two foremost levels of pattern preparation: separation of NPs with protein corona from the unbound proteins and the digestion of corona proteins. Taken collectively, proteomics analysis of porcine ISGylation substrates revealed putative useful roles of ISG15 and novel host ISGylation targets which will finally be concerned in mobile antiviral responses.

Separation strategies comparable to centrifugation, magnetic separation, and chromatography and three digestion strategies (in-gel, in-solution, and on-particle) are described with particular emphasis paid on their benefits and downsides in addition to their affect on the outcome of identification. This paper additionally signifies the want for standardization of protein corona identification protocols, as some of the proteins could also be preferentially detected whereas making use of a selected digestion process.

Comparative proteomic analysis provides insight into the molecular mechanism of vegetative growth advantage in allotriploid Populus

Proteomic Analysis of ISGylation in Immortalized Porcine Alveolar Macrophage Cell Lines Induced by Type I Interferon

 

Interferon-stimulated gene product 15 (ISG15), a ubiquitin-like molecule, might be conjugated to protein substrates by means of a reversible course of often called ISGylation. ISG15 and ISGylation are each strongly upregulated by sort I interferons and play putative key roles in host innate immunity in opposition to viral an infection. However, the perform of ISGylation and identities of ISGylation substrates are largely unknown. Here, a novel monoclonal antibody (Mab) that particularly acknowledges porcine ISG15 (pISG15) was employed to seize ISG15-conjugated proteins from IFNs-stimulated porcine cell lysates.

Next, Mab-captured conjugates have been analyzed utilizing proteomics-based instruments to determine potential ISGylation protein targets in order to elucidate the roles of ISG15 and ISGylation in porcine cells. Subsequently, 190 putative ISGylation websites have been detected inside 98 recognized ISGylation candidates; a number of candidates contained a couple of ISGylation-modifiable lysine residue, together with pISG15 itself. Motif enrichment analysis of confirmed ISGylation websites demonstrated a average bias in direction of sure websites with particular upstream amino acid residues.

Active Recombinant Human CETP
7606-1000
EUR 4345

Active Recombinant Human CETP
7606-20
EUR 262

Active SIRT2, human recombinant
7698-10
EUR 262

Active SIRT2, human recombinant
7698-1000
EUR 4394

Active SIRT2, human recombinant
7698-50
EUR 457

Active SIRT7, human recombinant
7846-10
EUR 218

Active SIRT7, human recombinant
7846-50
EUR 588

Irisin, Active, human recombinant
7852-10
EUR 370

Irisin, Active, human recombinant
7852-50
EUR 1077

HER2, Active, Human Recombinant
8011-5
EUR 240

HER2, Active, Human Recombinant
8011-50
EUR 1132

PRMT1, human recombinant (Active)
4865-10
EUR 153

PRMT1, human recombinant (Active)
4865-1000
EUR 3834

PRMT1, human recombinant (Active)
4865-50
EUR 392

GAPDH, Active, human recombinant
P1100-10
EUR 142

GAPDH, Active, human recombinant
P1100-50
EUR 392

Activin-A Human Recombinant Protein, Active
PROTP08476-2 Regular: 10ug
EUR 317
Description: Active form Activin-A Human Recombinant produced in e.coli is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 117 amino acids and having a molecular weight of 26.2kDa.;The Active form Activin-A is purified by standard chromatographic techniques.

Activin-B Human Recombinant Protein, Active
PROTP09529 Regular: 10ug
EUR 317
Description: Activin B human Recombinant produced in Nicotiana benthamiana plant is a beta-B single chain (aa 293-406) containing 123 amino acids (molecular formula C615H910N178O177S12). Activin B is fused to a 10-His-tag at the N-terminal having the total molecular mass of 14kDa and purified by standard chromatographic techniques.

Recombinant MeV Active Nucleocapsid Protein
VAng-Lsx0400-inquire inquire Ask for price
Description: Measles Active Nucleocapsid, recombinant protein from E. coli.

Activin-A Human Recombinant Protein, Plant-Active
PROTP08476-3 Regular: 5ug
EUR 317
Description: Active form Activin-A Human Recombinant produced in Plant is a homodimeric, glycosylated, polypeptide chain containing 2 x 116 amino acids and having a molecular weight of 27.4kDa.;The Active form Activin-A is fused to a 6-His tag at N-terminus and purified by standard chromatographic techniques.

Purified Recombinant Human BMP3 protein, Biologically active
BMP35-R-10 10 ug
EUR 408

Purified Recombinant Human BMP4 protein, Biologically active,
BMP45-R-10 10 ug
EUR 895

Purified Recombinant Human BMP4 protein, Biologically active
BMP45-R-5 5 ug
EUR 529

Purified Recombinant Human BMP6 protein, Biologically active
BMP65-R-20 20 ug
EUR 895

Recombinant purified, human NFkB-p65 protein, active
NFKB651-R-5 5 ug
EUR 651

Purified, recombinant Human TACE control protein (active)
TACE15-R-10 10 ug
EUR 712

Human Recombinant VEGF121 Protein (Sf9), biologically active
VEGF24-R-10 10 ug
EUR 445

Human Recombinant VEGF121 Protein (Sf9), biologically active
VEGF24-R-100 100 ug
EUR 2425

Human Recombinant VEGF121 Protein (E.Coli), biologically active
VEGF25-R-10 10 ug
EUR 445

Human Recombinant VEGF121 Protein (E.Coli), biologically active
VEGF25-R-100 100 ug
EUR 2425

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-10 10 ug
EUR 445

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-100 100 ug
EUR 2242

Human Recombinant VEGF165 Protein (E.Coli), biologically active
VEGF26-R-1000 1000 ug
EUR 9185

Human Recombinant VEGF165 Protein (Sf9), biologically active
VEGF27-R-10 10 ug
EUR 445

Human Recombinant VEGF165 Protein (HEK), biologically active
VEGF27-R-100 100 ug
EUR 2425

Human Recombinant VEGF165 Protein (Sf9), biologically active
VEGF27-R-1000 1000 ug
EUR 9185

Active Cathepsin S, human recombinant
7526-10
EUR 338

Active Cathepsin S, human recombinant
7526-50
EUR 1126

Active Cathepsin S, human recombinant
7526-500
EUR 9130

Active Cathepsin B, human recombinant
7580-1000
EUR 9783

Active Cathepsin B, human recombinant
7580-5
EUR 294

Active Cathepsin B, human recombinant
7580-50
EUR 1132

Cathepsin K, Active, human recombinant
7600-5
EUR 392

Cathepsin K, Active, human recombinant
7600-50
EUR 2279

MMP-9, Active, human recombinant
7867-1000
EUR 501

MMP-9, Active, human recombinant
7867-500
EUR 332

MMP-14, Active, Human Recombinant
8009-10
EUR 316

MMP-14, Active, Human Recombinant
8009-50
EUR 805

Active Cathepsin D, Human Recombinant
9229-10
EUR 245

Active Cathepsin D, Human Recombinant
9229-100
EUR 1132

Active Cathepsin D, Human Recombinant
9229-50
EUR 735

MMP-9, Active, Human Recombinant
P1567-10 10 µg
EUR 348

MMP-9, Active, Human Recombinant
P1567-50 50 µg
EUR 510

5-Lipoxygenase, Active, Human Recombinant
P1373-200
EUR 316

Recombinant Human Activin-A Active
7-00004 1ug Ask for price

Recombinant Human Activin-A Active
7-00005 5ug Ask for price

Recombinant Human Activin-A Active
7-00006 100µg Ask for price

Recombinant Human Activin-B Active
7-00010 1ug Ask for price

Recombinant Human Activin-B Active
7-00011 5ug Ask for price

Recombinant Human Activin-B Active
7-00012 100µg Ask for price

GLO1 Human, Glyoxalase-I Human Recombinant Protein, Active
PROTQ04760-1 Regular: 10ug
EUR 317
Description: Glyoxalase-I Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 184 amino acids and having a molecular mass of 20.7 kDa. ;Glyoxalase-1 is purified by proprietary chromatographic techniques.

CST3 Human, Cystatin-C Human Recombinant Protein, Active
PROTQ6FGW9-1 Regular: 10ug
EUR 317
Description: Cystatin-C Human Recombinant produced in HEK cells is a non-glycosylated monomer, having a molecular weight of approximately 13kDa.;The Cystatin-C is purified by proprietary chromatographic techniques.

MGLL Human, Monoglyceride Lipase Human Recombinant Protein, Active
PROTQ99685-1 Regular: 5ug
EUR 317
Description: MGLL Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 333 amino acids (1-313 a.a.) and having a molecular mass of 36.4kDa. The MGLL is purified by proprietary chromatographic techniques.

GDA Human, Guanine Deaminase Human Recombinant Protein, Active
PROTQ9Y2T3-2 Regular: 10ug
EUR 317
Description: GDA Human Recombinant produced in E. coli is a single polypeptide chain containing 477 amino acids (1-454) and having a molecular mass of 53kDa.;GDA is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

CSTA Human, Cystatin-A Human Recombinant Protein, Active
PROTP01040 Regular: 20ug
EUR 317
Description: Cystatin A Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 118 amino acids (1-98a.a.) and having a molecular mass of 13.1 kDa.;The Cystatin A is fused to a 20 amino acid His tag at N-terminus and purified by proprietary chromatographic techniques.

Human, Activin-A Human Recombinant Protein, HEK-Active
PROTP08476-1 Regular: 10ug
EUR 317
Description: Activin-A Human Recombinant produced in HEK cells is a non-glycosylated disulfide-linked homodimer, having a total molecular weight of 25kDa.;The Activin-A is purified by proprietary chromatographic techniques.

GLUL Human, Glutamine Synthetase Human Recombinant Protein, Active
PROTP15104-1 Regular: 10ug
EUR 317
Description: GLUL Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 373 amino acids (1-373) and having a molecular mass of 42kDa.

PGP Human, Phosphoglycolate Phosphatase Human Recombinant Protein, Active
PROTA6NDG6-1 Regular: 10ug
EUR 317
Description: PGP Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 345 amino acids (1-321a.a) and having a molecular mass of 36.5kDa.;PGP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Human CellExp? HDAC6, Human Recombinant, Active
P1265-50
EUR 446

Human CellExp? HDAC8, Human Recombinant, Active
P1266-50
EUR 446

Human CellExp? HDAC11, Human Recombinant, Active
P1267-50
EUR 446

Human SOD Protein (Active)
20-abx060221
  • EUR 314.00
  • EUR 732.00
  • EUR 1295.00
  • 100 ug
  • 1 mg
  • 2 mg

Active Human HSP70 Protein
SPR-103A 0.05 mg
EUR 300
Description: His tagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP70 Protein
SPR-103B 0.1 mg
EUR 388
Description: His tagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP70 Protein
SPR-103C 2x0.1 mg
EUR 669
Description: His tagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP60 Protein
SPR-104A 0.05 mg
EUR 231
Description: His tagged recombinant human HSP60 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP60 Protein
SPR-104B 0.1 mg
EUR 387
Description: His tagged recombinant human HSP60 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP60 Protein
SPR-104C 2x0.1 mg
EUR 568
Description: His tagged recombinant human HSP60 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSC70 Protein
SPR-106A 0.05 mg
EUR 236
Description: His tagged recombinant human HSC70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSC70 Protein
SPR-106B 0.1 mg
EUR 310
Description: His tagged recombinant human HSC70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSC70 Protein
SPR-106C 2x0.1 mg
EUR 538
Description: His tagged recombinant human HSC70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP70 Protein
SPR-108A 0.05 mg
EUR 300
Description: Untagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP70 Protein
SPR-108B 0.1 mg
EUR 388
Description: Untagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP70 Protein
SPR-108C 2x0.1 mg
EUR 669
Description: Untagged recombinant human HSP70 Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP70 Protein
SPR-115A 0.05 mg
EUR 346
Description: His tagged recombinant human HSP70 Protein expressed in Baculovirus/Hi5 cells for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP70 Protein
SPR-115B 0.1 mg
EUR 477
Description: His tagged recombinant human HSP70 Protein expressed in Baculovirus/Hi5 cells for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human HSP70 Protein
SPR-115C 2x0.1 mg
EUR 813
Description: His tagged recombinant human HSP70 Protein expressed in Baculovirus/Hi5 cells for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Mouse, GAPDH Mouse Recombinant Protein, Active
PROTP16858-1 Regular: 10ug
EUR 317
Description: GAPDH Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 356 amino acids (1-333a.a.) and having a molecular mass of 38.2kDa.;GAPDH is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Recombinant RSV Active SRC Protein [GST]
VAng-Lsx0456-inquire inquire Ask for price
Description: RSV Active SRC [GST], recombinant protein from Baculovirus.

Recombinant Human MAPK1, Active Protein, Untagged, E.coli-1ug
QP14023-1ug 1ug
EUR 155

Recombinant Human MAPK1, Active Protein, Untagged, E.coli-5ug
QP14023-5ug 5ug
EUR 201

Recombinant Human MAPK1, Active Protein, Untagged, E.coli-100ug
QP14023-EC-100ug 100ug
EUR 2059

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03937 3µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03938 10µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03939 20µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 1, Active
7-03946 2µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 1, Active
7-03947 10µg Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 1, Active
7-03948 100µg Ask for price

Purified (E.Coli) Recombinant Human BMP6 protein, Biologically active
BMP65-R-10 10 ug
EUR 529

Human Recombinant (E.Coli) Purified Noggin protein, biologically active
NOGN15-R-20 20 ug
EUR 469

PRMT1, mouse recombinant (Active)
4868-10
EUR 153

PRMT1, mouse recombinant (Active)
4868-1000
EUR 3834

PRMT1, mouse recombinant (Active)
4868-50
EUR 392

PDIA6 Human, Protein Disulfide Isomerase A6 Human Recombinant Protein, Active
PROTQ15084-1 Regular: 10ug
EUR 317
Description: PDIA6 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 442 amino acids (20-440 a.a.) and having a molecular mass of 48.5kDa. The PDIA6 is purified by proprietary chromatographic techniques.

PDIA4 Human, Protein Disulfide Isomerase A4 Human Recombinant Protein, Active
PROTP13667-1 Regular: 10ug
EUR 317
Description: PDIA4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 646 amino acids (21-645 a.a.) and having a molecular weight of 72.9kDa. The PDIA4 is fused to 21 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques.

PDIA3 Human, Protein Disulfide Isomerase A3 Human Recombinant Protein, Active
PROTP30101-1 Regular: 10ug
EUR 317
Description: PDIA3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 518 amino acids (25-505 a.a.) and having a molecular wieght of 58.5 kDa. The PDIA3 is fused to 37 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques.

TPI1 Human, Triosephosphate Isomerase 1 Human Recombinant Protein, Active
PROTP60174-1 Regular: 10ug
EUR 317
Description: TPI1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 269 amino acids (1-249a.a.) and having a molecular mass of 28.8kDa.;TPI1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

GNMT Human, Glycine N-Methyltransferase Human Recombinant Protein , Active
PROTQ14749-1 Regular: 10ug
EUR 317
Description: GNMT Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 315 amino acids (1-295 a.a) and having a molecular mass of 34.9kDa.;GNMT is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

GUK1 Human, Guanylate Kinase 1 Human Recombinant Protein, Active
PROTQ16774-1 Regular: 10ug
EUR 317
Description: GUK1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 217 amino acids (1-197 a.a.)and having a total molecular mass of 23.9 kDa. ;GUK1 is fused to a 20 amino acid His Tag at N-terminus and is purified by proprietary chromatographic techniques.

PHPT1 Human, Phosphohistidine Phosphatase 1 Human Recombinant Protein, Active
PROTQ9NRX4-1 Regular: 10ug
EUR 317
Description: PHPT1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 145 amino acids (1-125a.a.) and having a molecular mass of 15.9kDa.;PHPT1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

HPRT1 Human, Hypoxanthine-Guanine Phosphoribosyltransferase, Human Recombinant Protein, Active
PROTP00492-1 Regular: 10ug
EUR 317
Description: HPRT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 238 amino acids (1-218 a.a) and having a molecular mass of 26.7kDa. HPRT1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

GLUL Human, Glutamine Synthetase Human Recombinant Protein, His Active
PROTP15104-2 Regular: 10ug
EUR 317
Description: GLUL Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (1-373 a.a.) and having a molecular mass of 44.2 kDa. The GLUL is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

PGAM2 Human, Phosphoglycerate Mutase 2 Human Recombinant Protein, Active
PROTP15259-1 Regular: 10ug
EUR 317
Description: PGAM2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 273 amino acids (1-253) and having a molecular mass of 30.9kDa.;PGAM2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

PGAM1 Human, Phosphoglycerate Mutase 1 Human Recombinant Protein, Active
PROTP18669-1 Regular: 10ug
EUR 317
Description: PGAM1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 274 amino acids (1-254 a.a.) and having a molecular mass of 30.9 kDa. The PGAM1 is fused to a 20 amino acid His Tag at N-Terminus and purified by proprietary chromatographic techniques.

GPT Human, Glutamic-Pyruvate Transaminase Human Recombinant Protein, Active
PROTP24298-1 Regular: 3U
EUR 317
Description: Alanine Aminotransferase Human Recombinant produced in E.Coli is a homodimer, non-glycosylated, polypeptide chain containing 495a.a and having a molecular mass of 54,479 Dalton. The amino acid sequence is the same as that of native form of human liver ALT.;The ALT is purified by proprietary chromatographic techniques.

Active SIRT6 (GST-tagged), human recombinant
7697-100
EUR 479

Active SIRT6 (GST-tagged), human recombinant
7697-1000
EUR 3013

Active SIRT6 (GST-tagged), human recombinant
7697-20
EUR 272

Active SIRT6 (His-tagged), human recombinant
7699-100
EUR 425

Active SIRT6 (His-tagged), human recombinant
7699-1000
EUR 2545

Active SIRT6 (His-tagged), human recombinant
7699-20
EUR 218

Active Sonic Hedgehog (SHH), human recombinant
4010-100
EUR 936

Active Sonic Hedgehog (SHH), human recombinant
4010-1000
EUR 4432

Active Sonic Hedgehog (SHH), human recombinant
4010-25
EUR 327

Recombinant Human Alpha-1 Antitrypsin, Active
7-06361 20µg Ask for price

Recombinant Human Alpha-1 Antitrypsin, Active
7-06362 100µg Ask for price

Recombinant Human Alpha-1 Antitrypsin, Active
7-06363 1mg Ask for price

Recombinant Human Active Focal Adhesion Kinase
7-03955 1µg Ask for price

Recombinant Human Active Focal Adhesion Kinase
7-03956 5µg Ask for price

Recombinant Human Active Focal Adhesion Kinase
7-03957 10µg Ask for price

Active Human Caspases Group I, Active Human
K241-3-25
EUR 370

Active GST Protein
1243-1
EUR 175

Meanwhile, outcomes of Gene Ontology (GO)-based annotation and useful enrichment and protein-protein interplay (PPI) community analyses of porcine ISG15-conjugated substrate proteins indicated that these substrates have been primarily related to the host metabolism, particularly nucleotide metabolic pathways that finally might take part in mobile antiviral defenses. Notably, a number of ISGs (MX1, IFIT1, OAS1, ISG15 and putative ISG15 E3 ligase Herc6) have been additionally recognized as putative ISGylation substrates inside a regulatory loop involving ISGylation of ISGs themselves.